Eating a diet rich in both soy protein and isoflavones can protect menopausal
women from bone weakening and osteoporosis, according to the results
of a preliminary study presented today at the Society for Endocrinology
annual conference in Edinburgh.
Osteoporosis is a common condition where bones become brittle and fragile from
tissue loss, causing 9 million fractures worldwide every year. In women,
bone loss occurs most quickly in the years immediately after menopause because
they produce less of the sex hormone oestrogen, which protects against bone loss.
women from bone weakening and osteoporosis, according to the results
of a preliminary study presented today at the Society for Endocrinology
annual conference in Edinburgh.
Osteoporosis is a common condition where bones become brittle and fragile from
tissue loss, causing 9 million fractures worldwide every year. In women,
bone loss occurs most quickly in the years immediately after menopause because
they produce less of the sex hormone oestrogen, which protects against bone loss.
Soybean foods contain chemicals known as isoflavones that are similar in structure
to oestrogen and so could theoretically protect women against osteoporosis by
mimicking the action of oestrogen.
to oestrogen and so could theoretically protect women against osteoporosis by
mimicking the action of oestrogen.
In this study, researchers from the University of Hull gave two hundred women
in early menopause a daily supplement containing soy protein with 66mg
of isoflavones or a supplement with soy protein alone for six months.
The researchers investigated changes in the women's bone activity by measuring
certain proteins (βCTX and P1NP) in their blood.
in early menopause a daily supplement containing soy protein with 66mg
of isoflavones or a supplement with soy protein alone for six months.
The researchers investigated changes in the women's bone activity by measuring
certain proteins (βCTX and P1NP) in their blood.
They found that the women on the soy diet with isoflavones had significantly
lower levels of βCTX than the women on soy alone, suggesting that their rate
of bone loss was slowing down and lowering their risk of developing osteoporosis.
Women taking soy protein with isoflavones were also found to have decreased risk
of cardiovascular disease than those taking soy alone.
lower levels of βCTX than the women on soy alone, suggesting that their rate
of bone loss was slowing down and lowering their risk of developing osteoporosis.
Women taking soy protein with isoflavones were also found to have decreased risk
of cardiovascular disease than those taking soy alone.
Lead author of the study Thozhukat Sathyapalan said: "We found that soy protein
and isoflavones are a safe and effective option for improving bone health in women
during early menopause. The actions of soy appear to mimic that of conventional osteoporosis drugs."
and isoflavones are a safe and effective option for improving bone health in women
during early menopause. The actions of soy appear to mimic that of conventional osteoporosis drugs."
"The 66 mg of isoflavone that we use in this study is equivalent to eating an
oriental diet, which is rich in soy foods. In contrast, we only get around 2-16 mg
of isoflavone with the average western diet."
oriental diet, which is rich in soy foods. In contrast, we only get around 2-16 mg
of isoflavone with the average western diet."
"Supplementing our food with isoflavones could lead to a significant decrease
in the number of women being diagnosed with osteoporosis."
in the number of women being diagnosed with osteoporosis."
Researchers next aim to investigate the long-term health consequences of using
soy protein and isoflavones supplements, and whether it may also have benefits
beyond bone health.
soy protein and isoflavones supplements, and whether it may also have benefits
beyond bone health.
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